A Long-Distance Relationship between RNAi and Polycomb
نویسندگان
چکیده
RNA interference (RNAi) pathways can result in sequence-specific transcriptional gene silencing on the level of chromatin. In this issue of Cell, Grimaud et al. (2006) reveal that the RNAi machinery is required for long-distance physical interactions between chromosomes mediated by the Polycomb repressive complex. These results suggest that the RNAi machinery may regulate higher-order nuclear organization.
منابع مشابه
RNAi Components Are Required for Nuclear Clustering of Polycomb Group Response Elements
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ورودعنوان ژورنال:
- Cell
دوره 124 شماره
صفحات -
تاریخ انتشار 2006